When one is diagnosed with Alzheimer’s disease, the medical care provider may prescribe medication. Unfortunately, there is not yet a cure. The treatment medication may slow down the disease, but like other prescription medications, there are always potential side effects. It may work for a few years or it may work for just a few months. There are only four treatment medications currently being used for Alzheimer’s disease that are approved by the U.S. Food and Drug Administration .

From the Fischer Center for Alzheimer’s Research Foundation, the four treatment medications are:

* Cognex is rarely prescribed due to serious side effects, including possible liver damage.

Excelon and Aricept are used for the early stages of Alzheimer’s disease, whereas Namenda and Razadyne/Reminyl are prescribed for moderate to severe Alzheimer’s disease. In each case, the treatment medications it will not halt the disease in the long term.

Brain Tour from Alzheimer's Association (click image)

Just what is Alzheimer’s disease (AD)? Everyone seems to agree that it is the most common form of dementia accounting for at least half of all dementia cases. (See previous post on discussion of dementia). There is also agreement that in advanced Alzheimer’s disease, a person cannot function intellectually and socially. According to the Mayo Clinic, “Alzheimer’s disease is not a part of normal aging, but the risk of the disorder increases with age. About 5 percent of people between the ages of 65 and 74 have Alzheimer’s disease, while nearly half the people over the age of 85 have Alzheimer’s.”

What is happening in the brain that is causing a person not to be able to function intellectually and socially? Take the “Brain Tour” on the left and notice the shrinkage of the brain as well as the tangles. Just looking at those pictures explains the confusion, doesn’t it?

According to the Mayo Clinic, there are currently three major areas that doctors depend on to make a diagnosis:

1. Lab tests
2. Neuropsychological testing (extensive assessment of thinking and memory skills)
3. Brain scans
   • Magnetic resonance imaging (MRI)
   • Computerized tomography (CT)
   • Positron emission tomography (PET)

Although memory assessments should always be conducted by a medical practitioner, here are two quick paper and pencil tests. The first was published by Times Online (UK) called the “Five Minute Alzheimer’s Test.” The second one is on the Web site of a well-known Alzheimer’s drug, but it states, “This screening tool cannot be used to tell if your loved one has a medical problem, only whether he or she should be tested.” It was adapted from Galvin JE, et al. The AD8, a brief informant interview to detect dementia. Neurology 2005:65:559-564.

Once again, do not draw any conclusions from these memory tests. As discussed by Carrie Hill, Ph.D. in “What you Need to Know about Screenings for Memory Problems,” she states:

1. A memory screening should not be used to make a diagnosis
2. A memory screening does not replace a diagnostic workup
3. Memory screenings should only be performed by qualified professionals
4. Memory screenings should be confidential and provide follow-up resources
5. Memory screenings can be used to establish a baseline
6. Opinions differ on the value of memory screenings. Here she talks about the different views of the two leading non-profit Alzheimer’s organizations — Alzheimer’s Foundation of America and Alzheimer’s Association.

In our next blog post next week, we will look at the most recent diagnosis tools. In the meantime, have you done your Sudoku for today?